Like anything Mayo related, the pace is akin to molasses; you will practice the virtue of patience during the process. Typically after about a week or two of initially applying your application is sent to a hiring manager and then anywhere between two to four weeks later you will get a rejection email or called for an interview. The interview happens soon thereafter, but if it is during the beginning of the process you may have to wait a week or three for all of the interviews to be done.
The interview process is mostly to strictly behavioral based and it involves a panel, ranging in three people to a dozen or more. They ask, you respond. Depending on how quick you can think on your feet to answer their sometimes seemingly irrelevant questions, you may or may not like the interview. I found that the questions did little to weed out those who would work well or not work well as they focused too much on feel good aspects and not enough on work ethic.
With that being said, the interviewers were all friendly, professional, and pleasant.