Numerous - there is a significant lack of leadership, integrity and professionalism.
Leadership team fears the CEO because he is irrational and sporadic.
He's too arrogant to take advice from anyone who doesn't agree with him, and too inexperienced to run an effective company.
Have decreased from ~60 to ~40 employees in 2 years. Have also had significant turnover amongst senior team members in last 3-5 years. Many others on the verge of leaving.